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Page 1
Fragment-based drug nanoaggregation reveals drivers of self-assembly.
Nat Commun. 2023 Dec 14;14(1):8340. doi: 10.1038/s41467-023-43560-0.
Nat Commun. 2023.
PMID: 38097573
Free PMC article.
Targeted drug delivery strategies for precision medicines.
Manzari MT, Shamay Y, Kiguchi H, Rosen N, Scaltriti M, Heller DA.
Manzari MT, et al.
Nat Rev Mater. 2021 Apr;6(4):351-370. doi: 10.1038/s41578-020-00269-6. Epub 2021 Feb 2.
Nat Rev Mater. 2021.
PMID: 34950512
Free PMC article.
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Tumor-targeted nanoparticles improve the therapeutic index of BCL2 and MCL1 dual inhibition.
Bala Tannan N, Manzari MT, Herviou L, Da Silva Ferreira M, Hagen C, Kiguchi H, Manova-Todorova K, Seshan V, de Stanchina E, Heller DA, Younes A.
Bala Tannan N, et al. Among authors: manzari mt.
Blood. 2021 Apr 15;137(15):2057-2069. doi: 10.1182/blood.2020008017.
Blood. 2021.
PMID: 33067607
Free PMC article.
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Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models.
Manzari MT, Anderson GR, Lin KH, Soderquist RS, Çakir M, Zhang M, Moore CE, Skelton RN, Fèvre M, Li X, Bellucci JJ, Wardell SE, Costa SA, Wood KC, Chilkoti A.
Manzari MT, et al.
Sci Adv. 2019 Sep 4;5(9):eaaw9162. doi: 10.1126/sciadv.aaw9162. eCollection 2019 Sep.
Sci Adv. 2019.
PMID: 31517048
Free PMC article.
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Triepitopic antibody fusions inhibit cetuximab-resistant BRAF and KRAS mutant tumors via EGFR signal repression.
Spangler JB, Manzari MT, Rosalia EK, Chen TF, Wittrup KD.
Spangler JB, et al. Among authors: manzari mt.
J Mol Biol. 2012 Sep 28;422(4):532-44. doi: 10.1016/j.jmb.2012.06.014. Epub 2012 Jun 15.
J Mol Biol. 2012.
PMID: 22706026
Free PMC article.
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